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Control of Physical and Biological Properties

Materials used for tissue regeneration must be designed with precise physical and biological properties.

Mosaic's proprietary and patented technology provides precise control of the material's physical properties. For example, using the same basic chemistry, we can tune the modulus of elasticity to yield materials that are stiff for bone applications or soft for skin applications.

Similarly, Mosaic's click chemistry allows for covalent or non-covalent incorporation of biological factors such as proteins, peptides and nucleic acids, thereby providing the necessary signals for tissue regeneration and matrix degradation.

Mosaic's platform technology provides these advantages while also employing simple combinatorial techniques to identify ideal formulations for specific applications.

Mosaic's Advantages

Versatile Chemistry

  • Mosaic's patented click chemistry enables a nearly limitless combination of individual components without having to “reinvent the wheel” with each new formulation.

Bioresponsive

  • The incorporation of enzymatically degradable components allows Mosaic's materials to respond to the patient’s individual rate of healing.

Known Material Compositions

  • Mosaic materials replicate the physical and biochemical properties of native extracellular matrices while utilizing fully synthetic components. This approach allows the reliable manufacturing of materials with precise, predictable properties and eliminates the potential for immune responses that can occur with animal-derived materials.

“Perfect-Fit” Application

  • Mosaic's materials can be applied as a viscous liquid and cured in place. This provides full integration of the scaffold with the surrounding tissue, allowing the cells and biological factors necessary for the rapid regeneration of native tissues to migrate directly into the matrix.