Technology

 

Mosaic products are based on its patented thiol-ene click chemistry and proprietary modular polymer platform.  These technologies provide Mosaic with the unprecedented flexibility to create a range of novel biomaterials that are ideally suited to applications ranging from nano-particles to drug delivery matrices to scaffolds for tissue repair and regeneration.

Patented Thiol-Ene Click Chemistry

Thiol-Ene Chemistry

  • Safe: Mosaic’s thiol-ene chemistry does not react with or modify proteins, nucleic acids, cells, and tissues.
  • Fast: Reactions complete within seconds.
  • Controlled: Photo-initiation allows for spatial and temporal control of reactions.
  • Precise: Click chemistry reactions results in step growth matrices that provide precise control over the network structure and material properties.
  • Robust: pH-independent and not inhibited by oxygen.

Modular Platform for Creating Novel Biomaterials

Thiol-Ene Network

  • Versatile: Biomaterials can be created from a range of components, including synthetic components such as PEGs, PLGA, and natural components such as proteins, peptides, hyaluronic acid, and nucleic acids.
  • Bioresponsive: Biomaterials can be built to have specific degradation mechanisms allowing the creation of bioresponsive materials.
  • Bioactive: Proteins, nucleic acids, and cells can be encapsulated or incorporated into the material, allowing the creation of bioactive materials.
  • Biocompatible: Well defined breakdown products that can be easily cleared from the body
  • Flexible: Biomaterials can be rapidly formed in place (for example to fill a cartilage or bone defect) or can be reproducibly formed in a manufacturing process.